SAM-e 400

Jarrow Formulas' SAM-e 400 pharmaceutical grade, stabilized SAM-e is a full 400mg elemental SAM-e from 800mg of SAM-e tosylate disulfate. SAM-e 400 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product. 

SAM-e is a chiral molecule and therefore consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive.
Jarrow Formulas' SAM-e is made naturally by microbiological fermentation and then specially processed to preserve 68-80% (S,S) SAM-e, the highest active level available.

SAM-e (S-Adenosylmethionine) is an amino acid derivative that has been clinically proven to benefit brain and joint function. Found in all living cells, SAM-e is also called activated methionine (an essential amino acid) since it is formed by the combining of ATP with methionine. SAM-e has undergone dozens of trials involving thousands of patients. Researchers studying the beneficial effects of SAM-e have identified the following benefits of SAM-e: 

• Joint Strength - SAM-e supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue, including glucosamine and the chondroitin sulfates, are sulfated by SAM-e metabolites.  

• Brain Metabolism -SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-dopa, dopamine and related hormones, epinephrine and phosphatidylcholine (a component of lecithin). 

• Liver - SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione-S-transferase), which are substances important for liver function.

• Longevity - Methylation of DNA appears to be important in the suppression of errors in DNA replication.Demethylation of DNA is considered a contributor to the aging process. Proper methylation through substances such as SAM-e positively influences longevity.

WARNING: Individuals using prescribed medications such as antidepressants, including Serotonin Re-Uptake Inhibitors and MAO Inhibitors, should consult a physician before using. Individuals with bi-polar disorder or manic depression should not use SAM-e.

Usage: Take 1 to 2 tablets per day on an empty stomach as directed by your qualified healthcare professional.

Supplement Facts

Serving Size: 1

Servings per container: 1

Tablets Per Container: 30

Amount Per Serving:

This is a statement of nutritional support. This statement has not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Store in a cool, dry place. 
KEEP OUT OF REACH OF CHILDREN.